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Common fruit flies resistant to carbofuran

Common fruit flies (Drosophila melanogaster) have developed resistance to carbofuran insecticide, according to Spanish researchers. The insecticide has been applied on fruit trees for decades. Fruit flies have also mutated to resist benzaldehyde organic compounds. The uncovered mutation is an insertion in the genome of a moving DNA fragment or transposon, which often causes harmful mutations to the organism. The researchers from the Spanish University Pompeu Fabra’s superior council of scientific investigations (CSIC-UPF - Barcelona) found that the mutation affects gene CG11699, and that those flies with greater expression of the gene possess higher enzyme activity and greater ability to metabolise xenobiotics and derived substances, the researchers say. The work is relevant to other flies, they add. The study has been published in the journal, PLoS Genetics.

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