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US grant for new mosquito insecticides

The US National Institute of Allergy and Infectious Diseases has awarded a $3.5 million grant to US university Virginia Tech (Blacksburg, Virginia) and the US computational chemistry company, Molsoft (La Jolla, California), to develop novel insecticides for the control of malaria-spreading mosquitoes ( Anopheles gambiae). The researchers are seeking to develop products suitable for use on bed nets and effective against pyrethroid-resistant mosquitoes. They have modified the structures of acetylcholinesterase-targeting insecticides to lower their mammalian toxicity. Patent applications have been filed and commercial interest expressed, the researchers say.



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