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Low-dose effects of EDs under study in EU

A study on the possible “low-dose effects” of endocrine disrupting chemicals is under way and is due to be completed by the end of 2015, says the European Food Safety Authority (EFSA). The work is part of the ongoing project to establish criteria for identification and regulation of agrochemicals and biocides that may be endocrine disruptors (EDs). Hypotheses about low-dose effects, relating to levels below those typically used in toxicological testing, and irregular/non-linear dose-response relationships of chemicals challenge key concepts in risk assessment, the EFSA says. It notes that its 2013 scientific opinion on ED definitions did not address the low-dose issue, but recognised that it warranted more in-depth investigation. As a result, it commissioned the current study, which is being carried out by the French and Austrian food safety authorities, ANSES and AGES.



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