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US EPA/ NIH non-animal testing pact

The US EPA and the National Institutes of Health (NIH) have agreed to collaborate on the development of new testing procedures for pesticides and other chemicals that rely less on whole animal studies. The organisations aim to use high-throughput screening to test suspected toxic compounds using cells and isolated molecular targets instead of laboratory animals. The new approach is expected to generate data more relevant to humans, expand the number of chemicals tested and reduce the time, cost and use of animals in testing. Full implementation of this "paradigm shift in toxicity testing" will require a substantial validation effort, which is expected to take many years.

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